1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, 9H-fluoren-9-ylmethyl ester
1-Fmoc-2-(hydroxymethyl)piperidine
CAS: 170867-95-5
Molecular Formula: C21H23NO3
1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, 9H-fluoren-9-ylmethyl ester - Names and Identifiers
1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, 9H-fluoren-9-ylmethyl ester - Physico-chemical Properties
| Molecular Formula | C21H23NO3 |
| Molar Mass | 337.41 |
1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, 9H-fluoren-9-ylmethyl ester - Introduction
1-Fmoc-2-(hydroxymethyl)piperidine is a chemical compound with a variety of properties and uses.
In terms of properties, it is a white or off-white crystalline solid with high melting point and thermal stability. It is soluble in some organic solvents, such as dimethyl sulfoxide and difluorotoluene, but insoluble in water. It is a molecule that can form hydrogen bonds and has certain catalytic activity.
In Terms of Use, 1-Fmoc-2-(hydroxymethyl)piperidine is mainly used as a protecting group in organic synthesis. It can protect the piperidine amine group from other reactants in the chemical reaction. The protecting group can then be removed by appropriate conditions to reactivate the piperidine amine group, if desired. In addition, it can also be used to synthesize organic compounds such as peptides and drugs.
In terms of preparation method, 1-Fmoc-2-(hydroxymethyl)piperidine can be synthesized by reacting 2-hydroxymethylpiperidine with 1-fluoro-2-methoxydiphenylketone. The reaction is usually carried out in an organic solvent and requires an appropriate temperature and reaction time.
In terms of safety information, 1-Fmoc-2-(hydroxymethyl)piperidine is a chemical that requires safe operating procedures in laboratories and industrial production. It may cause irritation and damage to the human body, and direct contact with skin and eyes should be avoided. Wear personal protective equipment such as gloves and goggles during operation. In addition, waste should be stored and disposed of properly to avoid harm to the environment.
In terms of properties, it is a white or off-white crystalline solid with high melting point and thermal stability. It is soluble in some organic solvents, such as dimethyl sulfoxide and difluorotoluene, but insoluble in water. It is a molecule that can form hydrogen bonds and has certain catalytic activity.
In Terms of Use, 1-Fmoc-2-(hydroxymethyl)piperidine is mainly used as a protecting group in organic synthesis. It can protect the piperidine amine group from other reactants in the chemical reaction. The protecting group can then be removed by appropriate conditions to reactivate the piperidine amine group, if desired. In addition, it can also be used to synthesize organic compounds such as peptides and drugs.
In terms of preparation method, 1-Fmoc-2-(hydroxymethyl)piperidine can be synthesized by reacting 2-hydroxymethylpiperidine with 1-fluoro-2-methoxydiphenylketone. The reaction is usually carried out in an organic solvent and requires an appropriate temperature and reaction time.
In terms of safety information, 1-Fmoc-2-(hydroxymethyl)piperidine is a chemical that requires safe operating procedures in laboratories and industrial production. It may cause irritation and damage to the human body, and direct contact with skin and eyes should be avoided. Wear personal protective equipment such as gloves and goggles during operation. In addition, waste should be stored and disposed of properly to avoid harm to the environment.
Last Update：2024-04-09 21:50:46
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